Pränatale und transgenerationale Einflüsse · Kapitel 41 von 41

Quellenverzeichnis

Das Verzeichnis enthält alle 214 Quellen der Master-Liste (synthese.json) mit der in der Gesamtstudie verwendeten ID. Format: [sNN] Autoren (Jahr): Titel. Journal. PMID/DOI (bei Quellen ohne PMID und DOI die Internetadresse). Titel in anderen Sprachen als Englisch oder Deutsch stehen im Original, gefolgt von einer deutschen Übersetzung in Klammern; die in eckigen Klammern gesetzten Titel einzelner französischer Arbeiten sind die in PubMed geführten englischen Titelübersetzungen. Wo die Master-Liste keine Autoren nannte, wurden sie aus dem Europe-PMC-Eintrag ergänzt (s64, s80, s99); bei s132 nennt PubMed keine Autoren. Bei s12 fehlte die Zeitschrift in der Master-Liste und wurde aus dem Europe-PMC-Eintrag ergänzt.

  • [s01] Ait Bamai Y, Kishi R (2026): Exposure to Environmental Chemicals and Children's Health: Findings from the Hokkaido Study. Yakugaku Zasshi. PMID 41922249; DOI 10.1248/yakushi.25-00161-1.
  • [s02] Basak S et al. (2026): Transgenerational exposure to plastics-derived endocrine-disrupting bisphenol A and its analogs on male infertility: impact of gut dysbiosis and epigenetic regulation. Front Endocrinol (Lausanne). PMID 42181199; DOI 10.3389/fendo.2026.1799472.
  • [s03] Brix N, Ernst A, Gaml-Sørensen A, et al. (2026): Body fat percentage in relation to semen characteristics, testicular volume, and reproductive hormones. Hum Reprod. PMID 42526509; DOI 10.1093/humrep/deag104.
  • [s04] Di QN et al. (2026): 父源性环境内分泌干扰物的代际表观遗传调控:孕前暴露对子代健康研究进展 (Intergenerationale epigenetische Regulation durch väterliche umweltbedingte endokrine Disruptoren: Forschungsstand zur Wirkung präkonzeptioneller Exposition auf die Gesundheit der Nachkommen). 食品科学. URL https://www.spkx.net.cn/CN/abstract/abstract71823.shtml.
  • [s05] Eletri L; Joseph-Delaffon K; Dechartres A et al. (2026): Association between in utero exposure to acetaminophen and external genital tract malformations in boys and girls: a systematic review and meta-analysis. Hum Reprod. PMID 41615881; DOI 10.1093/humrep/deaf253.
  • [s06] Gaml-Sørensen A, Brix N, Ernst A, et al. (2026): Intrauterine growth and male reproductive health. Andrology. PMID 42366700; DOI 10.1111/andr.70287.
  • [s07] Gaml-Sørensen A, Brix N, Tøttenborg SS, et al. (2026): Season of birth and variations in male reproductive health. Andrology. PMID 40297929; DOI 10.1111/andr.70052.
  • [s08] Hauberg FV et al. (2026): Maternal Consumption of Artificially Sweetened Beverages in Pregnancies and Biomarkers of Fecundity in Adult Sons. Andrology. PMID 42454414; DOI 10.1111/andr.70317.
  • [s09] Hull SD; Hougaard KS; Toft G et al. (2026): Fetal exposure to a mixture of endocrine-disrupting chemicals and biomarkers of male fecundity: A population-based cohort study. Andrology. PMID 40220336; DOI 10.1111/andr.70039.
  • [s10] La Vignera S, Condorelli RA (2026): The global decline in sperm count and testosterone levels. Antioxidants. PMID 42352084; DOI 10.3390/antiox15060778.
  • [s11] Negri F, Boeri L, Pozzi E et al. (2026): Low testosterone in primary infertile men is associated with a history of maternal obesity during pregnancy: Findings from a cross-sectional study. Andrology. PMID 40366358; DOI 10.1111/andr.70054.
  • [s12] Oguri T et al. (2026): Integrating Sperm Microscopy, Environmental Exposures, and Lifestyle Factors for Male Fertility Analysis: Protocol for the Nippon Semen and Environmental Exposure Database (N-SEED) Cross-Sectional Study. JMIR Res Protoc. PMID 41996690; DOI 10.2196/93803.
  • [s13] Perry MJ, Meddis A, Young HA, et al. (2026): In utero and childhood exposure to organochlorines and perfluorinated chemicals in relation to sperm aneuploidy in adulthood. Environ Health. PMID 42067914; DOI 10.1186/s12940-026-01303-w.
  • [s14] Sacco D et al. (2026): Dioxin, an endocrine disruptor, induces long term effects on DNA methylation in men after in-utero exposure. Minerva Endocrinol (Torino). PMID 41553716; DOI 10.23736/s2724-6507.25.04276-9.
  • [s15] Stokholm MV, Ernst A, Håberg SE et al. (2026): Prenatal exposure to parental smoking and infertility in sons and daughters: a cohort study. Hum Reprod. PMID 41739999; DOI 10.1093/humrep/deag011.
  • [s16] Tatsuta N et al.; Japan Environment and Children's Study Group (2026): Cohort profile: The Japan Environment and Children's Study. Int J Epidemiol. PMID 42576399; DOI 10.1093/ije/dyag146.
  • [s17] Thomsen AH, Gaml-Sørensen A, Tøttenborg SS, et al. (2026): Parental educational attainment at birth and biomarkers of male fecundity. Andrology. PMID 41536044; DOI 10.1111/andr.70175.
  • [s18] Ulaganathan G, Murphy SK (2026): Endocrine disruption and male fertility. Curr Environ Health Rep. PMID 42234061; DOI 10.1007/s40572-026-00545-7.
  • [s19] Wang K et al. (2026): Sertoli cell oxidative stress as a convergent hazard endpoint for environmental toxicants. Redox Biol. PMID 42762776; DOI 10.1016/j.redox.2026.104407.
  • [s20] Wang QH, Ye JJ, Chen ZY et al. (2026): Current risk factors for male infertility and semen parameters: an umbrella review of systematic reviews and meta-analyses. Asian J Androl. PMID 41527944; DOI 10.4103/aja202552.
  • [s21] Zidan NE et al. (2026): Endocrine-Disrupting Pesticides as Drivers of Human Disease: Mechanistic Toxicology and Life-Course Health Effects. Int J Mol Sci. PMID 42589584; DOI 10.3390/ijms27156928.
  • [s22] Al-Omari B, Alam Z, Farhat J, Mohamed SA, et al. (2025): Associations between maternal overweight and obesity with cesarean section delivery in Middle East and North Africa region: a systematic review, meta-analysis, and attributable risk. Syst Rev. PMID 41372993; DOI 10.1186/s13643-025-03016-6.
  • [s23] Andreasen SM, Lund LC, Hagen CP, et al. (2025): Maternal urinary paracetamol concentrations and self-reported paracetamol use in mid-gestation: Association to reduced anogenital distance in offspring from infancy to 9 years. Reprod Toxicol. PMID 40374128; DOI 10.1016/j.reprotox.2025.108946.
  • [s24] Chen J et al. (2025): Tracing impacts of prenatal exposure to bisphenol analogues on child anogenital distance development: a birth-cohort study. J Hazard Mater. PMID 40022929; DOI 10.1016/j.jhazmat.2025.137730.
  • [s25] Ciarloni A, Delli Muti N, Sacco S et al. (2025): Genetic, Epigenetic, and Non-Genetic Factors in Testicular Dysgenesis Syndrome: A Narrative Review. Genes (Basel). PMID 41595460; DOI 10.3390/genes17010040.
  • [s26] Cui J et al. (2025): Mechanisms and reversibility of nicotine-induced spermatogenesis impairment and DNA methylation changes. Commun Biol. PMID 40665023; DOI 10.1038/s42003-025-08493-y.
  • [s27] Haervig KK et al. (2025): Paternal pre-conceptional smoking and semen quality in the adult son. Andrology. PMID 37885366; DOI 10.1111/andr.13550.
  • [s28] He Y, Zhang Z, Zheng Q, et al. (2025): Paternal alcohol exposure affected offspring mesenteric artery via ROS-Cacna1c and DNA hypomethylation. J Hypertens. PMID 39791443; DOI 10.1097/HJH.0000000000003947.
  • [s29] Kishi R, Ikeda A, Ketema RM (2025): The potential health risks of exposure to environmental chemicals - Global implications for future generations. Proc Jpn Acad Ser B Phys Biol Sci. PMID 40222897; DOI 10.2183/pjab.101.015.
  • [s30] Liao H et al. (2025): Epigenetic effects of paternal environmental exposures and experiences on offspring phenotypes. Trends Genet. PMID 40467385; DOI 10.1016/j.tig.2025.04.015.
  • [s31] Minhas S et al. (2025): European Association of Urology guidelines on male sexual and reproductive health: 2025 update on male infertility. Eur Urol. PMID 40118737; DOI 10.1016/j.eururo.2025.02.026.
  • [s32] Mizuno Y et al. (2025): Associations between urinary phthalate metabolite mixtures, semen quality, and serum reproductive hormone levels in Japanese men seeking fertility treatment. Reprod Toxicol. PMID 40460943; DOI 10.1016/j.reprotox.2025.108957.
  • [s33] Ragheb A, Abdelbary A, Massoud A, Abd Elkhalek M, et al. (2025): Evaluating the effect of smoking and its cessation on semen parameters. Reprod Fertil. PMID 41051027; DOI 10.1530/RAF-24-0135.
  • [s34] Rahban R, Santa-Ramírez HA, Senn A et al. (2025): Exploring geographical differences in semen quality of young men using spatial dependence analysis. Hum Reprod. PMID 41022404; DOI 10.1093/humrep/deaf182.
  • [s35] Skerrett-Byrne DA, Ashton LM, Nixon B, Morgan PJ (2025): Determinants of male fertility in the Western Pacific Region: environmental, biological, and lifestyle influences. Lancet Reg Health West Pac. PMID 41541617; DOI 10.1016/j.lanwpc.2025.101716.
  • [s36] Tatsuta N et al. (2025): Direct and indirect effects of smoking during pregnancy on child development: The Japan Environment and Children's Study. Sci Rep. PMID 40410275; DOI 10.1038/s41598-025-02684-7.
  • [s37] Uldbjerg CS; Lim YH; Beck AL et al. (2025): Exposure to per- and polyfluoroalkyl substances during fetal development and risk of testicular germ cell cancer in adulthood. Environ Int. PMID 40902259; DOI 10.1016/j.envint.2025.109762.
  • [s38] Xi J et al. (2025): Associations of prenatal exposure to legacy and emerging PFAS with anogenital distance growth trajectories during early childhood: a prospective cohort study. J Hazard Mater. PMID 40555014; DOI 10.1016/j.jhazmat.2025.138999.
  • [s39] Yamamoto M et al. (2025): Association between Maternal Exposure to Per- and Polyfluoroalkyl Substances and Childhood Growth Trajectories up to 4 Years of Age: The Japan Environment and Children's Study. Environ Sci Technol. PMID 41134985; DOI 10.1021/acs.est.5c09583.
  • [s40] Capelo MF, Monteiro PB, Anastácio BM (2024): Effects of major analgesics on male fertility: A systematic literature review. JBRA Assist Reprod. PMID 38546117; DOI 10.5935/1518-0557.20240020.
  • [s41] Clemmensen PJ, Brix N, Schullehner J, Toft G, et al. (2024): Maternal use of nitrosatable drugs during pregnancy and adult male reproductive health: a population-based cohort study. Andrology. PMID 38488298; DOI 10.1111/andr.13625.
  • [s42] Farag AGA, Badr EA, Kholif AOA, Khalifa MN, et al. (2024): Serum and seminal plasma levels of lead and arsenic in cigarette smokers and their relation to the semen parameters. Biol Trace Elem Res. PMID 38180596; DOI 10.1007/s12011-023-04039-7.
  • [s43] Gaml-Sorensen A et al. (2024): Maternal pre-pregnancy BMI and reproductive health in adult sons: a study in the Danish National Birth Cohort. Hum Reprod. PMID 37935951; DOI 10.1093/humrep/dead230.
  • [s44] Huang K, Gaml-Sørensen A, Brix N, et al. (2024): Birth by caesarean section and semen quality in adulthood. Reprod Health. PMID 38459587; DOI 10.1186/s12978-024-01761-w.
  • [s45] Itoh M et al. (2024): Association between prenatal tobacco exposure and attention-deficit/hyperactivity disorder related characteristics at 6 and 8 years: a birth cohort in Japan. BMJ Open. PMID 39725438; DOI 10.1136/bmjopen-2024-087406.
  • [s46] Langergaard MJ et al. (2024): Maternal coffee consumption and biomarkers of reproductive health in young, adult sons: a cohort study. Reprod Toxicol. PMID 39159852; DOI 10.1016/j.reprotox.2024.108689.
  • [s47] Laursen TQ et al. (2024): Maternal intake of paracetamol during pregnancy and biomarkers of male fecundity in young adult sons. Reprod Toxicol. PMID 38815769; DOI 10.1016/j.reprotox.2024.108626.
  • [s48] Park HJ (2024): Addressing South Korea's Critical Challenge: Exploration of the Low Birth Rate Issue from a Medical Perspective and Role of Andrologists. World J Mens Health. PMID 38449459; DOI 10.5534/wjmh.240014.
  • [s49] Sharpe RM (2024): Endocrine disruption and male reproductive disorders: unanswered questions. Hum Reprod. PMID 38926156; DOI 10.1093/humrep/deae143.
  • [s50] Titus et al. (2024): Benign and Malignant Outcomes in the Offspring of Females Exposed In Utero to DES: NCI Third Generation Study. Cancers. PMID 39061214; DOI 10.3390/cancers16142575.
  • [s51] Zhu MY et al. (2024): Spouse smoking cessation benefits the pregnancy outcomes of the women with polycystic ovary syndrome. Zhonghua Nan Ke Xue. PMID 40783868.
  • [s52] Ahn C, Jeung EB (2023): Endocrine-Disrupting Chemicals and Disease Endpoints. Int J Mol Sci. PMID 36982431; DOI 10.3390/ijms24065342.
  • [s53] Beck AL et al. (2023): Maternal exposure to cigarette smoke during pregnancy and testicular cancer in offspring: a systematic review and meta-analysis. Life (Basel). PMID 36983774; DOI 10.3390/life13030618.
  • [s54] Carter T et al. (2023): Paternal preconception modifiable risk factors for adverse pregnancy and offspring outcomes: a review of contemporary evidence from observational studies. BMC Public Health. PMID 36927694; DOI 10.1186/s12889-023-15335-1.
  • [s55] Dahlen CR, Amat S, Caton JS, et al. (2023): Paternal effects on fetal programming. Anim Reprod. PMID 37700908; DOI 10.1590/1984-3143-AR2023-0076.
  • [s56] Dornfeldt MM, Andersen AN, Hougaard KS, et al. (2023): Maternal fever during pregnancy and male offspring reproductive health. Andrology. PMID 36415019; DOI 10.1111/andr.13345.
  • [s57] Gaml-Sørensen A, Brix N, Hærvig KK et al. (2023): Maternal vitamin D levels and male reproductive health: a population-based follow-up study. Eur J Epidemiol. PMID 36952117; DOI 10.1007/s10654-023-00987-5.
  • [s58] Gaml-Sørensen A, Brix N, Høyer BB, et al (2023): Maternal intake of folate and folic acid during pregnancy and markers of male fecundity: A population-based cohort study. Andrology. PMID 36524586; DOI 10.1111/andr.13364.
  • [s59] Gaml-Sørensen A, Brix N, Tøttenborg SS, et al. (2023): Selection bias in a male-offspring cohort investigating fecundity: is there reason for concern? Hum Reprod. PMID 36370427; DOI 10.1093/humrep/deac241.
  • [s60] Henriksen LS et al. (2023): Maternal phthalate exposure during pregnancy and testis function of young adult sons. Sci Total Environ. PMID 36736395; DOI 10.1016/j.scitotenv.2023.161914.
  • [s61] Langergaard MJ et al. (2023): Maternal age at menarche and reproductive health in young adult men: a cohort study. Hum Reprod. PMID 36303450; DOI 10.1093/humrep/deac231.
  • [s62] Lee JH, Cho SE (2023): Effects of Endocrine-Disrupting Chemicals on Human Health. Lab Med Online. DOI 10.47429/lmo.2023.13.3.129.
  • [s63] Levine H et al. (2023): Temporal trends in sperm count: a systematic review and meta-regression analysis of samples collected globally in the 20th and 21st centuries. Hum Reprod Update. PMID 36377604; DOI 10.1093/humupd/dmac035.
  • [s64] Xue S, Liu L, Dong M, et al. (2023): Prenatal exposure to bisphenol AF induced male offspring reproductive dysfunction by triggering testicular innate and adaptive immune responses. Ecotoxicol Environ Saf. PMID 37216864; DOI 10.1016/j.ecoenv.2023.115030.
  • [s65] Roach AN et al. (2023): Preconception paternal alcohol exposure decreases IVF embryo survival and pregnancy success rates in a mouse model. Mol Hum Reprod. PMID 36637195; DOI 10.1093/molehr/gaad002.
  • [s66] Rogers RE et al. (2023): Prenatal exposure to diethylstilbestrol has long-lasting, transgenerational impacts on fertility and reproductive development. Toxicol Sci. PMID 37471692; DOI 10.1093/toxsci/kfad066.
  • [s67] Shen X et al. (2023): Prenatal exposure to fine particulate matter and newborn anogenital distance: a prospective cohort study. Environ Health. PMID 36755317; DOI 10.1186/s12940-023-00969-w.
  • [s68] Thomsen AH et al. (2023): Maternal alcohol intake in early pregnancy and biomarkers of fecundity in adult sons: A cohort study. Reprod Toxicol. PMID 37217037; DOI 10.1016/j.reprotox.2023.108396.
  • [s69] Auger J et al. (2022): Spatiotemporal trends in human semen quality. Nat Rev Urol. PMID 35978007; DOI 10.1038/s41585-022-00626-w.
  • [s70] Bazid HAS, Attia AM, Yousef AM, Fawal AN, et al. (2022): Evaluating the serum and seminal plasma levels of zinc and cadmium in smokers and their relation to the semen parameters. Biol Trace Elem Res. PMID 33860457; DOI 10.1007/s12011-021-02720-3.
  • [s71] Chen Q et al. (2022): Preconception reproductive health and birth outcome cohort in Chongqing: the cohort profile. Zhonghua Liu Xing Bing Xue Za Zhi. PMID 35856211; DOI 10.3760/cma.j.cn112338-20220219-00134.
  • [s72] Cinzori ME, Strakovsky RS (2022): Effects of elevated maternal adiposity on offspring reproductive health. J Endocr Soc. PMID 36438545; DOI 10.1210/jendso/bvac163.
  • [s73] Grison S, Legendre A, Svilar L, et al. (2022): Multigenerational exposure to uranium changes sperm metabolome in rats. Int J Mol Sci. PMID 35955476; DOI 10.3390/ijms23158349.
  • [s74] Haervig KK et al. (2022): Maternal exposure to per- and polyfluoroalkyl substances (PFAS) and male reproductive function in young adulthood: combined exposure to seven PFAS. Environ Health Perspect. PMID 36197086; DOI 10.1289/EHP10285.
  • [s75] Hærvig KK, Petersen KU, Giwercman A, et al. (2022): Fetal exposure to maternal cigarette smoking and male reproductive function in young adulthood. Eur J Epidemiol. PMID 35476275; DOI 10.1007/s10654-022-00869-2.
  • [s76] Holmboe SA, Scheutz Henriksen L, Frederiksen H, et al. (2022): Prenatal exposure to phenols and benzophenones in relation to markers of male reproductive function in adulthood. Front Endocrinol. PMID 36568115; DOI 10.3389/fendo.2022.1071761.
  • [s77] Kortenkamp A, Scholze M, Ermler S, et al. (2022): Combined exposures to bisphenols, polychlorinated dioxins, paracetamol, and phthalates as drivers of deteriorating semen quality. Environ Int. PMID 35691715; DOI 10.1016/j.envint.2022.107322.
  • [s78] Liu Y, Zhang C, Liu Y, et al. (2022): Paternal nicotine/ethanol/caffeine mixed exposure induces offspring rat dysplasia. Int J Mol Sci. PMID 36499404; DOI 10.3390/ijms232315081.
  • [s79] Meneghini MA et al. (2022): Diet-induced maternal obesity and overnutrition cause a decrease in the sperm quality of the offspring. J Nutr Biochem. PMID 35181443; DOI 10.1016/j.jnutbio.2022.108966.
  • [s80] Wensink MJ, Lu Y, Tian L, et al. (2022): Preconception antidiabetic drugs in men and birth defects in offspring: a nationwide cohort study. Ann Intern Med. PMID 35344380; DOI 10.7326/M21-4389.
  • [s81] Østergaard CS, Ernst A, Gaml-Sørensen A, et al. (2022): Use of paracetamol (acetaminophen) as a nonprescription analgesic and semen quality in young men. Andrology. PMID 34779581; DOI 10.1111/andr.13129.
  • [s82] Petersen KU et al. (2022): PFAS and male reproductive function in young adulthood; a cross-sectional study. Environ Res. PMID 35318009; DOI 10.1016/j.envres.2022.113157.
  • [s83] Tadokoro-Cuccaro R et al. (2022): Maternal paracetamol intake during pregnancy: impacts on offspring reproductive development. Front Toxicol. PMID 35499038; DOI 10.3389/ftox.2022.884704.
  • [s84] Wang H, Liu J, Gao J, et al. (2022): Perinatal exposure to nicotine alters sperm RNA profiles in rats. Front Endocrinol. PMID 35600600; DOI 10.3389/fendo.2022.893863.
  • [s85] Yang L et al. (2022): Maternal cigarette smoking before or during pregnancy increases the risk of birth congenital anomalies: a population-based retrospective cohort study of 12 million mother-infant pairs. BMC Med. PMID 35012532; DOI 10.1186/s12916-021-02196-x.
  • [s86] El-Shahawy O, Labib K, Stevens E, Kahn LG, et al. (2021): Exclusive and dual cigarette and hookah smoking is associated with adverse perinatal outcomes among pregnant women in Cairo, Egypt. Int J Environ Res Public Health. PMID 34948585; DOI 10.3390/ijerph182412974.
  • [s87] Hammer B et al. (2021): Preconceptional smoking alters spermatozoal miRNAs of murine fathers and affects offspring's body weight. Int J Obes. PMID 34002034; DOI 10.1038/s41366-021-00798-2.
  • [s88] Kheirallah KA, Shugaa Addin N, Alolimat MM (2021): Trends of maternal waterpipe, cigarettes, and dual tobacco smoking in Jordan. A decade of lost opportunities. PLoS One. PMID 34242237; DOI 10.1371/journal.pone.0253655.
  • [s89] Kishi R et al. (2021): Hokkaido birth cohort study on environment and children's health: cohort profile 2021. Environ Health Prev Med. PMID 34022817; DOI 10.1186/s12199-021-00980-y.
  • [s90] Rodprasert W, Toppari J, Virtanen HE (2021): Endocrine Disrupting Chemicals and Reproductive Health in Boys and Men. Front Endocrinol. PMID 34690925; DOI 10.3389/fendo.2021.706532.
  • [s91] Strohsnitter WC, Hyer M, Bertrand KA et al. (2021): Prenatal Diethylstilbestrol Exposure and Cancer Risk in Males. Cancer Epidemiol Biomarkers Prev. PMID 34272263; DOI 10.1158/1055-9965.epi-21-0234.
  • [s92] Agarwal MM (2020): Gestational diabetes in the Arab Gulf countries: sitting on a land-mine. Int J Environ Res Public Health. PMID 33322416; DOI 10.3390/ijerph17249270.
  • [s93] Albeitawi S, Hamadneh J, Al-Shatanawi TN, Al Mehaisen L, et al. (2020): Effect of hookah (water pipe) smoking on semen parameters. Andrologia. PMID 32609391; DOI 10.1111/and.13723.
  • [s94] Baydilli et al. (2020): How does body mass index affect semen parameters and reproductive hormones in infertile males? Turk J Urol. PMID 32053100; DOI 10.5152/tud.2020.19243.
  • [s95] Haervig KK et al. (2020): Fetal exposure to paternal smoking and semen quality in the adult son. Andrology. PMID 32150347; DOI 10.1111/andr.12782.
  • [s96] Hart RJ (2020): The Impact of Prenatal Exposure to Bisphenol A on Male Reproductive Function. Front Endocrinol. PMID 32547491; DOI 10.3389/fendo.2020.00320.
  • [s97] Kaushik A, Anand S, Bhartiya D (2020): Altered biology of testicular VSELs and SSCs by neonatal endocrine disruption. Stem Cell Rev Rep. PMID 32592162; DOI 10.1007/s12015-020-09996-3.
  • [s98] Keglberg Haervig K et al. (2020): Fetal Programming of Semen Quality (FEPOS) cohort - a DNBC male-offspring cohort. Clin Epidemiol. PMID 32765110; DOI 10.2147/CLEP.S242631.
  • [s99] Pereira MRF, Aleixo JF, Cavalcanti LF, et al. (2020): Can maternal exposure to paracetamol impair reproductive parameters of male rat offspring? Reprod Toxicol. PMID 31926975; DOI 10.1016/j.reprotox.2019.12.007.
  • [s100] Rahban R, Nef S (2020): Regional difference in semen quality of young men: a review on the implication of environmental and lifestyle factors during fetal life and adulthood. Basic Clin Androl. PMID 33072332; DOI 10.1186/s12610-020-00114-4.
  • [s101] Sun X et al. (2020): Prenatal exposure to residential PM2.5 and anogenital distance in infants at birth: a birth cohort study from Shanghai, China. Environ Pollut. PMID 32380398; DOI 10.1016/j.envpol.2020.114684.
  • [s102] Wautier A, Tournaire M, Devouche E, et al. (2020): Genital tract and reproductive characteristics in daughters of women and men prenatally exposed to diethylstilbestrol (DES). Therapie. PMID 31806244; DOI 10.1016/j.therap.2019.10.004.
  • [s103] Akison LK, Moritz KM, Reid N (2019): Adverse reproductive outcomes associated with fetal alcohol exposure: a systematic review. Reproduction. PMID 30653461; DOI 10.1530/REP-18-0607.
  • [s104] Chigrinets SV, Bryukhin GV (2019): Effect of endocrine disrupting chemicals bisphenol A and triclosan on semen quality. Kazan Medical Journal. DOI 10.17816/KMJ2019-629.
  • [s105] Garlantézec R, Multigner L, Oliva A (2019): Maternal smoking during pregnancy, semen characteristics and reproductive hormone levels in men consulting for couple infertility. Andrologia. PMID 31571259; DOI 10.1111/and.13423.
  • [s106] Rahban R, Priskorn L, Senn A, et al. (2019): Semen quality of young men in Switzerland: a nationwide cross-sectional population-based study. Andrology. PMID 31115178; DOI 10.1111/andr.12645.
  • [s107] Rossitto M et al. (2019): Intergenerational effects on mouse sperm quality after in utero exposure to acetaminophen and ibuprofen. FASEB J. PMID 29979629; DOI 10.1096/fj.201800488RRR.
  • [s108] Youngson NA, Uddin GM, Das A, et al. (2019): Impacts of obesity, maternal obesity and nicotinamide mononucleotide supplementation on sperm quality in mice. Reproduction. PMID 31226694; DOI 10.1530/REP-18-0574.
  • [s109] Yu C et al. (2019): Maternal smoking during pregnancy and risk of cryptorchidism: a systematic review and meta-analysis. Eur J Pediatr. PMID 30465272; DOI 10.1007/s00431-018-3293-9.
  • [s110] Axelsson J et al. (2018): Association between paternal smoking at the time of pregnancy and the semen quality in sons. PLoS One. PMID 30462692; DOI 10.1371/journal.pone.0207221.
  • [s111] Hart RJ, Doherty DA, Keelan JA, et al. (2018): The impact of antenatal bisphenol A exposure on male reproductive function at 20-22 years of age. Reprod Biomed Online. PMID 29291929; DOI 10.1016/j.rbmo.2017.11.009.
  • [s112] Kalem et al. (2018): Maternal nutrition and reproductive functions of female and male offspring. Reproduction. PMID 30306771; DOI 10.1530/REP-18-0070.
  • [s113] Kjersgaard C et al. (2018): Lifestyle in pregnancy and cryptorchidism in sons: a study within two large Danish birth cohorts. Clin Epidemiol. PMID 29593434; DOI 10.2147/CLEP.S150657.
  • [s114] Kristensen DM; Desdoits-Lethimonier C; Mackey AL et al. (2018): Ibuprofen alters human testicular physiology to produce a state of compensated hypogonadism. Proc Natl Acad Sci U S A. PMID 29311296; DOI 10.1073/pnas.1715035115.
  • [s115] Miyashita C et al. (2018): Sex-related differences in the associations between maternal dioxin-like compounds and reproductive and steroid hormones in cord blood: The Hokkaido study. Environ Int. PMID 29753148; DOI 10.1016/j.envint.2018.04.046.
  • [s116] Nemtsova MV, Dantsev IS, Mikhaylenko DS, Loran OV (2018): Genetic Aspects of Testicular Dysgenesis Syndrome and Associated Conditions. Cancer Urology (Onkourologiya). DOI 10.17650/1726-9776-2018-14-3-92-106.
  • [s117] Odintsova VV, Saifitdinova AF, Naumova OYu (2018): Maternal Smoking and DNA Methylation Disorders in Children at Early Developmental Stages. Akusherstvo i Ginekologiya. DOI 10.18565/aig.2018.9.5-12.
  • [s118] Petersen MS, Halling J, Jørgensen N, et al. (2018): Reproductive function in a population of young Faroese men with elevated exposure to PCBs and PFAS. Int J Environ Res Public Health. PMID 30200252; DOI 10.3390/ijerph15091880.
  • [s119] Priskorn L et al. (2018): Average sperm count remains unchanged despite reduction in maternal smoking: results from a large cross-sectional study with annual investigations over 21 years. Hum Reprod. PMID 29659832; DOI 10.1093/humrep/dey090.
  • [s120] Schantz SL, Waters KM et al. (2018): Systematic reviews and meta-analyses of human and animal evidence of prenatal diethylhexyl phthalate exposure and changes in male anogenital distance. J Toxicol Environ Health B. PMID 30199328; DOI 10.1080/10937404.2018.1505354.
  • [s121] Sun X et al. (2018): Maternal exposure to bisphenol A and anogenital distance throughout infancy: a longitudinal study from Shanghai, China. Environ Int. PMID 30223203; DOI 10.1016/j.envint.2018.08.055.
  • [s122] Tournaire M; Devouche E; Epelboin S et al. (2018): Birth defects in children of men exposed in utero to diethylstilbestrol (DES). Therapie. PMID 29609831; DOI 10.1016/j.therap.2018.02.007.
  • [s123] Ben Maamar M; Lesné L; Hennig K et al. (2017): Ibuprofen results in alterations of human fetal testis development. Sci Rep. PMID 28281692; DOI 10.1038/srep44184.
  • [s124] Culha MG, Serefoglu EC (2017): Prolonged exposure to acetaminophen during pregnancy reduces testosterone production by the human fetal testis (editorial). Ann Transl Med. PMID 28603733; DOI 10.21037/atm.2017.01.57.
  • [s125] Dai J et al. (2017): Paternal nicotine exposure defines different behavior in subsequent generation via hyper-methylation of mmu-miR-15b. Sci Rep. PMID 28779169; DOI 10.1038/s41598-017-07920-3.
  • [s126] Gurney J; Richiardi L; McGlynn KA et al. (2017): Analgesia use during pregnancy and risk of cryptorchidism: a systematic review and meta-analysis. Hum Reprod. PMID 28333256; DOI 10.1093/humrep/dex047.
  • [s127] Hay-Schmidt A et al. (2017): Prenatal exposure to paracetamol/acetaminophen and precursor aniline impairs masculinisation of male brain and behaviour. Reproduction. PMID 28559473; DOI 10.1530/REP-17-0165.
  • [s128] Jenkins TG et al. (2017): Cigarette smoking significantly alters sperm DNA methylation patterns. Andrology. PMID 28950428; DOI 10.1111/andr.12416.
  • [s129] Lind DV et al. (2017): Maternal use of mild analgesics during pregnancy associated with reduced anogenital distance in sons: a cohort study of 1027 mother-child pairs. Hum Reprod. PMID 27852690; DOI 10.1093/humrep/dew285.
  • [s130] Smarr MM et al. (2017): Male urinary paracetamol and semen quality. Andrology. PMID 28853221; DOI 10.1111/andr.12413.
  • [s131] Virtanen HE, Jørgensen N, Toppari J (2017): Semen quality in the 21st century. Nat Rev Urol. PMID 28050014; DOI 10.1038/nrurol.2016.261.
  • [s132] Autoren nicht angegeben (2016): Diethylstilbestrol (DES): also harms the third generation. Prescrire Int. PMID 30758926.
  • [s133] Bonde JP; Flachs EM; Rimborg S et al. (2016): The epidemiologic evidence linking prenatal and postnatal exposure to endocrine disrupting chemicals with male reproductive disorders: a systematic review and meta-analysis. Hum Reprod Update. PMID 27655588; DOI 10.1093/humupd/dmw036.
  • [s134] Fisher BG, Thankamony A, Hughes IA, Ong KK, Dunger DB, Acerini CL (2016): Prenatal paracetamol exposure is associated with shorter anogenital distance in male infants. Hum Reprod. PMID 27609981; DOI 10.1093/humrep/dew196.
  • [s135] Hart RJ; Doherty DA; Keelan JA et al. (2016): Early Life Events Predict Adult Testicular Function; Data Derived From the Western Australian (Raine) Birth Cohort. J Clin Endocrinol Metab. PMID 27340882; DOI 10.1210/jc.2016-1646.
  • [s136] Kristensen et al. (2016): Analgesic use - prevalence, biomonitoring and endocrine and reproductive effects. Nat Rev Endocrinol. PMID 27150289; DOI 10.1038/nrendo.2016.55.
  • [s137] Odacı et al. (2016): Effects of prenatal exposure to a 900 MHz electromagnetic field on 60-day-old rat testis and epididymal sperm quality. Biotech Histochem. PMID 26472053; DOI 10.3109/10520295.2015.1060356.
  • [s138] Sharma R et al. (2016): Cigarette smoking and semen quality: a new meta-analysis examining the effect of the 2010 WHO laboratory methods for the examination of human semen. Eur Urol. PMID 27113031; DOI 10.1016/j.eururo.2016.04.010.
  • [s139] Skakkebaek NE, Rajpert-De Meyts E, Buck Louis GM et al. (2016): Male Reproductive Disorders and Fertility Trends: Influences of Environment and Genetic Susceptibility. Physiol Rev. PMID 26582516; DOI 10.1152/physrev.00017.2015.
  • [s140] Yang YJ, Hong YP, Chae SA (2016): Reduction in semen quality after mixed exposure to bisphenol A and isobutylparaben in utero and during lactation periods. Hum Exp Toxicol. PMID 26519482; DOI 10.1177/0960327115608927.
  • [s141] Axelsson J et al. (2015): Prenatal phthalate exposure and reproductive function in young men. Environ Res. PMID 25743932; DOI 10.1016/j.envres.2015.02.024.
  • [s142] Eladak S; Grisin T; Moison D et al. (2015): A new chapter in the bisphenol A story: bisphenol S and bisphenol F are not safe alternatives to this compound. Fertil Steril. PMID 25475787; DOI 10.1016/j.fertnstert.2014.11.005.
  • [s143] Harlev A, Agarwal A, Gunes SO, Shetty A, du Plessis SS (2015): Smoking and Male Infertility: An Evidence-Based Review. World J Mens Health. PMID 26770934; DOI 10.5534/wjmh.2015.33.3.143.
  • [s144] Hart RJ, Doherty DA, McLachlan RI, et al (2015): Testicular function in a birth cohort of young men. Hum Reprod. PMID 26409015; DOI 10.1093/humrep/dev244.
  • [s145] Kalfa N; Paris F; Philibert P et al. (2015): Is Hypospadias Associated with Prenatal Exposure to Endocrine Disruptors? A French Collaborative Controlled Study of a Cohort of 300 Consecutive Children Without Genetic Defect. Eur Urol. PMID 26007639; DOI 10.1016/j.eururo.2015.05.008.
  • [s146] van den Driesche S, Macdonald J, Anderson RA, et al. (2015): Prolonged exposure to acetaminophen reduces testosterone production by the human fetal testis in a xenograft model. Sci Transl Med. PMID 25995226; DOI 10.1126/scitranslmed.aaa4097.
  • [s147] Zhang L et al. (2015): Maternal gestational smoking, diabetes, alcohol drinking, pre-pregnancy obesity and the risk of cryptorchidism: a systematic review and meta-analysis of observational studies. PLoS One. PMID 25798927; DOI 10.1371/journal.pone.0119006.
  • [s148] Cavalcante FS et al. (2014): The testis of the mice C57/BL6 offspring in adulthood have alterations due to maternal caffeine consumption. Acta Cir Bras. PMID 24474173; DOI 10.1590/S0102-86502014000100003.
  • [s149] Habert R; Muczynski V; Grisin T et al. (2014): Concerns about the widespread use of rodent models for human risk assessments of endocrine disruptors. Reproduction. PMID 24497529; DOI 10.1530/REP-13-0497.
  • [s150] Hakonsen LB, Ernst A, Ramlau-Hansen CH (2014): Maternal cigarette smoking during pregnancy and reproductive health in children: a review of epidemiological studies. Asian J Androl. PMID 24369132; DOI 10.4103/1008-682X.122351.
  • [s151] Hounsgaard ML; Håkonsen LB; Vested A et al. (2014): Maternal pre-pregnancy body mass index and pubertal development among sons. Andrology. PMID 24339440; DOI 10.1111/j.2047-2927.2013.00171.x.
  • [s152] Juul A, Almstrup K, Andersson AM, et al. (2014): Possible fetal determinants of male infertility. Nat Rev Endocrinol. PMID 24935122; DOI 10.1038/nrendo.2014.97.
  • [s153] Priskorn L; Jensen TK; Lindahl-Jacobsen R et al. (2014): Parental age at delivery and a man's semen quality. Hum Reprod. PMID 24578474; DOI 10.1093/humrep/deu039.
  • [s154] Sobinoff AP et al. (2014): Damaging legacy: maternal cigarette smoking has long-term consequences for male offspring fertility. Hum Reprod. PMID 25269568; DOI 10.1093/humrep/deu235.
  • [s155] Tournaire M; Epelboin S; Devouche E (2014): [Diethylstilbestrol story]. Therapie. PMID 24698194; DOI 10.2515/therapie/2014012.
  • [s156] Vested A et al. (2014): In utero exposure to persistent organochlorine pollutants and reproductive health in the human male. Reproduction. PMID 25190505; DOI 10.1530/REP-13-0488.
  • [s157] Axelsson J et al. (2013): The impact of paternal and maternal smoking on semen quality of adolescent men. PLoS One. PMID 23840528; DOI 10.1371/journal.pone.0066766.
  • [s158] Håkonsen LB et al. (2013): Maternal cigarette smoking during pregnancy and pubertal development in sons. Andrology. PMID 23335592; DOI 10.1111/j.2047-2927.2012.00038.x.
  • [s159] Iwamoto T et al. (2013): Semen quality of fertile Japanese men: a cross-sectional population-based study of 792 men. BMJ Open. PMID 23355656; DOI 10.1136/bmjopen-2012-002223.
  • [s160] Mazaud-Guittot S; Nicolas Nicolaz C; Desdoits-Lethimonier C et al. (2013): Paracetamol, aspirin, and indomethacin induce endocrine disturbances in the human fetal testis capable of interfering with testicular descent. J Clin Endocrinol Metab. PMID 24030937; DOI 10.1210/jc.2013-2531.
  • [s161] Mendiola J, Jørgensen N, Mínguez-Alarcón L, et al. (2013): Sperm counts may have declined in young university students in Southern Spain. Andrology. PMID 23307495; DOI 10.1111/j.2047-2927.2012.00058.x.
  • [s162] Reed CE; Fenton SE (2013): Exposure to diethylstilbestrol during sensitive life stages: a legacy of heritable health effects. Birth Defects Res C Embryo Today. PMID 23897597; DOI 10.1002/bdrc.21035.
  • [s163] Rolland M; Le Moal J; Wagner V et al. (2013): Decline in semen concentration and morphology in a sample of 26,609 men close to general population between 1989 and 2005 in France. Hum Reprod. PMID 23213178; DOI 10.1093/humrep/des415.
  • [s164] Vested A et al. (2013): Associations of in utero exposure to perfluorinated alkyl acids with human semen quality and reproductive hormones in adult men. Environ Health Perspect. PMID 23360585; DOI 10.1289/ehp.1205118.
  • [s165] Dewalque L; Charlier C (2012): [Masculine fertility threatened by the presence of endocrine disruptors in environment?]. Rev Med Liege. PMID 22891474.
  • [s166] Fernandez MF, Duran I, Olea N, Avivar C, Vierula M, Toppari J, Skakkebaek NE, Jørgensen N (2012): Semen quality and reproductive hormone levels in men from Southern Spain. Int J Androl. PMID 21332503; DOI 10.1111/j.1365-2605.2010.01131.x.
  • [s167] Håkonsen LB, Spano M, Bonde JP, et al. (2012): Exposures that may affect sperm DNA integrity: two decades of follow-up in a pregnancy cohort. Reprod Toxicol. PMID 22230645; DOI 10.1016/j.reprotox.2011.12.013.
  • [s168] Kristensen DM; Lesné L; Le Fol V et al. (2012): Paracetamol (acetaminophen), aspirin (acetylsalicylic acid) and indomethacin are anti-androgenic in the rat foetal testis. Int J Androl. PMID 22612476; DOI 10.1111/j.1365-2605.2012.01282.x.
  • [s169] Laubenthal J; Zlobinskaya O; Poterlowicz K et al. (2012): Cigarette smoke-induced transgenerational alterations in genome stability in cord blood of human F1 offspring. FASEB J. PMID 22730438; DOI 10.1096/fj.11-201194.
  • [s170] Barrett JR (2011): Window for dioxin damage: sperm quality in men born after the Seveso disaster. Environ Health Perspect. PMID 21531655; DOI 10.1289/ehp.119-a219b.
  • [s171] Cirillo PM, Cohn BA, Krigbaum NY, et al. (2011): Effect of maternal coffee, smoking and drinking behavior on adult son's semen quality. J Dev Orig Health Dis. PMID 25140488; DOI 10.1017/S2040174411000584.
  • [s172] Inserm (2011): Reproduction et environnement : une expertise collective de l'Inserm (communiqué de presse) (Fortpflanzung und Umwelt: eine kollektive Expertise des Inserm, Pressemitteilung). Zeitschrift nicht angegeben. URL https://presse.inserm.fr/wp-content/uploads/2011/04/EC_CP_reproduction_environnement_14042011v2.pdf.
  • [s173] Jacobsen K, Ramlau-Hansen CH, Thulstrup AM, et al. (2011): Maternal folic acid supplement intake and semen quality in Danish sons: a follow-up study. Fertil Steril. PMID 21664612; DOI 10.1016/j.fertnstert.2011.05.037.
  • [s174] Kristensen DM et al. (2011): Intrauterine exposure to mild analgesics is a risk factor for development of male reproductive disorders in human and rat. Hum Reprod. PMID 21059752; DOI 10.1093/humrep/deq323.
  • [s175] López Teijón M, Barceló D, Farré M, Martínez E, Temprano H, Álvarez JG (2011): Relación entre la exposición a disruptores endocrinos durante el período fetal y perinatal y la tasa de oligospermia (Zusammenhang zwischen der Exposition gegenüber endokrinen Disruptoren in der fetalen und perinatalen Phase und der Oligospermierate). Rev Int Androl 9(2):41-49. URL https://www.elsevier.es/es-revista-revista-internacional-andrologia-262-pdf-download-X1698031X11241162.
  • [s176] Mocarelli P et al. (2011): Perinatal exposure to low doses of dioxin can permanently impair human semen quality. Environ Health Perspect. PMID 21262597; DOI 10.1289/ehp.1002134.
  • [s177] Ravnborg TL et al. (2011): Prenatal and adult exposures to smoking are associated with adverse effects on reproductive hormones, semen quality, final height and body mass index. Hum Reprod. PMID 21335416; DOI 10.1093/humrep/der011.
  • [s178] Autoren nicht angegeben (2010): Mère fumeuse, enfants moins fertiles (Rauchende Mutter, weniger fruchtbare Kinder). Le Quotidien du Médecin. URL https://gynecologie-obstetrique.lequotidiendumedecin.fr/specialites/addictologie/mere-fumeuse-enfants-moins-fertiles.
  • [s179] Ramlau-Hansen CH et al. (2010): Maternal alcohol consumption during pregnancy and semen quality in the male offspring: two decades of follow-up. Hum Reprod. PMID 20587536; DOI 10.1093/humrep/deq140.
  • [s180] Sharpe RM (2010): Environmental/lifestyle effects on spermatogenesis. Philos Trans R Soc Lond B Biol Sci. PMID 20403879; DOI 10.1098/rstb.2009.0206.
  • [s181] Titus-Ernstoff L et al. (2010): Birth defects in the sons and daughters of women who were exposed in utero to diethylstilbestrol (DES). Int J Androl. PMID 20002218; DOI 10.1111/j.1365-2605.2009.01010.x.
  • [s182] Ouko LA, Shantikumar K, Knezovich J, et al. (2009): Effect of alcohol consumption on CpG methylation in the differentially methylated regions of H19 and IG-DMR in male gametes. Alcohol Clin Exp Res. PMID 19519716; DOI 10.1111/j.1530-0277.2009.00993.x.
  • [s183] Palmer JR et al. (2009): Urogenital abnormalities in men exposed to diethylstilbestrol in utero: a cohort study. Environ Health. PMID 19689815; DOI 10.1186/1476-069X-8-37.
  • [s184] Tuomisto J et al. (2009): Maternal smoking during pregnancy and testicular cancer in the sons: a nested case-control study and a meta-analysis. Eur J Cancer. PMID 19231156; DOI 10.1016/j.ejca.2009.01.017.
  • [s185] Paasch U, Salzbrunn A, Glander HJ, et al. (2008): Semen quality in sub-fertile range for a significant proportion of young men from the general German population. Int J Androl. PMID 18315714; DOI 10.1111/j.1365-2605.2007.00860.x.
  • [s186] Ramlau-Hansen CH et al. (2008): Semen quality according to prenatal coffee and present caffeine exposure: two decades of follow-up of a pregnancy cohort. Hum Reprod. PMID 18757446; DOI 10.1093/humrep/den331.
  • [s187] Rouiller-Fabre V; Lambrot R; Muczynski V et al. (2008): [Development and regulations of testicular functions in the human foetus]. Gynecol Obstet Fertil. PMID 18718803; DOI 10.1016/j.gyobfe.2008.06.022.
  • [s188] Fernandez MF, Olmos B, Granada A, et al. (2007): Human exposure to endocrine-disrupting chemicals and prenatal risk factors for cryptorchidism and hypospadias: a nested case-control study. Environ Health Perspect. PMID 18174944; DOI 10.1289/ehp.9351.
  • [s189] Fernández MF, Olmos B, Olea N (2007): Exposición a disruptores endocrinos y malformaciones del tracto urogenital masculino (criptorquidia e hipospadias) (Exposition gegenüber endokrinen Disruptoren und Fehlbildungen des männlichen Urogenitaltrakts (Kryptorchismus und Hypospadie)). Gac Sanit. PMID 18001666; DOI 10.1157/13112246.
  • [s190] Guzmán C, Zambrano E (2007): Endocrine disruptor compounds and their role in the developmental programming of the reproductive axis. Rev Invest Clin. PMID 17569302.
  • [s191] Iwamoto T, Nozawa S, Yoshiike M (2007): Semen quality of Asian men. Reprod Med Biol. PMID 29699277; DOI 10.1111/j.1447-0578.2007.00184.x.
  • [s192] Ramlau-Hansen CH et al. (2007): Is prenatal exposure to tobacco smoking a cause of poor semen quality? A follow-up study. Am J Epidemiol. PMID 17369608; DOI 10.1093/aje/kwm032.
  • [s193] Ramlau-Hansen CH, Nohr EA, Thulstrup AM, et al. (2007): Is maternal obesity related to semen quality in the male offspring? A pilot study. Hum Reprod. PMID 17704100; DOI 10.1093/humrep/dem219.
  • [s194] Ramlau-Hansen CH; Thulstrup AM; Bonde JP et al. (2007): Parental infertility and semen quality in male offspring: a follow-up study. Am J Epidemiol. PMID 17548784; DOI 10.1093/aje/kwm117.
  • [s195] Reina Bouvet B, Paparella CV, Feldman RN (2007): Efecto del tabaquismo sobre la espermatogénesis en hombres con infertilidad idiopática (Wirkung des Tabakrauchens auf die Spermatogenese bei Männern mit idiopathischer Infertilität). Arch Esp Urol 60(3):273-277. URL http://www.redalyc.org/articulo.oa?id=181013938007.
  • [s196] Brouwers MM et al. (2006): Hypospadias: a transgenerational effect of diethylstilbestrol? Hum Reprod. PMID 16293648; DOI 10.1093/humrep/dei398.
  • [s197] Mauduit C; Florin A; Amara S et al. (2006): [Long-term effects of environmental endocrine disruptors on male fertility]. Gynecol Obstet Fertil. PMID 16996771; DOI 10.1016/j.gyobfe.2006.08.010.
  • [s198] Storgaard L, Bonde JP, Olsen J (2006): Male reproductive disorders in humans and prenatal indicators of estrogen exposure. A review of published epidemiological studies. Reprod Toxicol. PMID 16005180; DOI 10.1016/j.reprotox.2005.05.006.
  • [s199] Jensen MS, Mabeck LM, Toft G, Thulstrup AM, Bonde JP (2005): Lower sperm counts following prenatal tobacco exposure. Hum Reprod. PMID 15919771; DOI 10.1093/humrep/dei110.
  • [s200] Palmer JR; Wise LA; Robboy SJ et al. (2005): Hypospadias in sons of women exposed to diethylstilbestrol in utero. Epidemiology. PMID 15951681; DOI 10.1097/01.ede.0000164789.59728.6d.
  • [s201] Jensen TK, Jørgensen N, Punab M, et al. (2004): Association of in utero exposure to maternal smoking with reduced semen quality and testis size in adulthood. Am J Epidemiol. PMID 14693659; DOI 10.1093/aje/kwh002.
  • [s202] Bamigboye AA; Morris J (2003): Oestrogen supplementation, mainly diethylstilbestrol, for preventing miscarriages and other adverse pregnancy outcomes. Cochrane Database Syst Rev. PMID 12918007; DOI 10.1002/14651858.CD004353.
  • [s203] Storgaard L et al. (2003): Does smoking during pregnancy affect sons' sperm counts? Epidemiology. PMID 12859027; DOI 10.1097/00001648-200305000-00006.
  • [s204] Skakkebaek NE, Rajpert-De Meyts E, Main KM (2001): Testicular dysgenesis syndrome: an increasingly common developmental disorder with environmental aspects. Hum Reprod. PMID 11331648; DOI 10.1093/humrep/16.5.972.
  • [s205] Guo YL, Hsu PC, Hsu CC, Lambert GH (2000): Semen quality after prenatal exposure to polychlorinated biphenyls and dibenzofurans. Lancet. PMID 11072947; DOI 10.1016/S0140-6736(00)02792-6.
  • [s206] Multigner L; Magistrini M; Ducot B et al. (2000): [Environment and secular sperm trend. Stallion's semen quality during the last two decades]. Rev Epidemiol Sante Publique. PMID 10992112.
  • [s207] Hemminki E, Gissler M, Meriläinen J (1999): Reproductive effects of in utero exposure to estrogen and progestin drugs. Fertil Steril. PMID 10360916; DOI 10.1016/s0015-0282(99)00140-5.
  • [s208] 香山不二雄, 岩井裕子 (1999): 環境ホルモンの健康影響 (Gesundheitliche Auswirkungen von Umwelthormonen). 保健婦雑誌. DOI 10.11477/mf.1662902014.
  • [s209] Jensen TK, Henriksen TB, Hjollund NH, et al. (1998): Adult and prenatal exposures to tobacco smoke as risk indicators of fertility among 430 Danish couples. Am J Epidemiol. PMID 9829871; DOI 10.1093/oxfordjournals.aje.a009576.
  • [s210] Wilcox AJ et al. (1995): Fertility in men exposed prenatally to diethylstilbestrol. N Engl J Med. PMID 7723797; DOI 10.1056/NEJM199505253322104.
  • [s211] Ratcliffe JM; Gladen BC; Wilcox AJ et al. (1992): Does early exposure to maternal smoking affect future fertility in adult males? Reprod Toxicol. PMID 1521002; DOI 10.1016/0890-6238(92)90192-v.
  • [s212] Drapier E (1984): [Fertility disorders attributable to the use of diethylstilbestrol during intrauterine life]. Rev Fr Gynecol Obstet. PMID 6397835.
  • [s213] Whitehead ED; Leiter E (1981): Genital abnormalities and abnormal semen analyses in male patients exposed to diethylstilbestrol in utero. J Urol. PMID 7463583; DOI 10.1016/s0022-5347(17)54895-8.
  • [s214] Gill WB et al. (1979): Association of diethylstilbestrol exposure in utero with cryptorchidism, testicular hypoplasia and semen abnormalities. J Urol. PMID 37351; DOI 10.1016/s0022-5347(17)56240-0.
Alle Kapitel und Anhänge (44)
  1. Das Wichtigste in Kürze
  2. Aufbau und Methodik dieser Studie
  3. 2.1 Fragestellung, Leitbegriffe und Expositionsfenster bis 2.6 Hodenvolumen, Hormone und DNA-Integrität
  4. 2.7 Wie Studien Effekte berichten: Effektmaße, Verzerrungen, Designs und 2.8 Die Geschichte der Forschungsfrage
  5. 2.9 Der Populationskontext: Sinken die Spermienzahlen, und was hat das mit der Pränatalfrage zu tun? bis 2.12 Quellen außerhalb der Master-Quellenliste (Transparenz)
  6. Zweck, Auswahl und Lesehinweise bis Paracetamol und andere Analgetika
  7. Hormonell wirksame Stoffe bis Zusammenschau: Was die Metaanalysen für die einzelnen Expositionen zeigen
  8. Gemeinsame methodische Grenzen bis Lücken und nicht belegbare Punkte dieses Kapitels
  9. Vorbemerkung zu Auswahl, Datengrundlage und Lesart
  10. 1.1 Spermienqualität, Hormone und Hodenvolumen der Söhne bis 1.3 Langzeitfolgen jenseits der Samenqualität: Fertilität, Hodenhochstand, Hodenkrebs und Entwicklung
  11. 1.4 Rauchen erwachsener Männer und Rauchen Schwangerer in Regionen mit Wasserpfeife
  12. 2. Alkohol der Mutter in der Schwangerschaft bis 5. Per- und polyfluorierte Alkylsubstanzen (PFAS)
  13. 6. Hormonell wirksame Stoffe: Dioxine, PCB, Phthalate, Bisphenole, Pestizide, Feinstaub und Mischungen und 7. Übergewicht der Mutter, Körpergewicht der Söhne und intrauterines Milieu
  14. 8. Diethylstilbestrol (DES) und andere Sexualhormone in der Schwangerschaft und 9. Väterliche Präkonzeptionsexposition
  15. 10. Weitere FEPOS-Analysen, Raine-Kohorte und Kohortenprofile und 11. Referenzstudien zur Samenqualität in der Allgemeinbevölkerung und Trendstudien
  16. 12. Gesamtübersicht der Beobachtungsstudien
  17. 1. Interventionsstudien und Nachbeobachtungen randomisierter Studien und 2. Fallserien und exponierte Gruppen im Vergleich
  18. 3. Leitlinien, Stellungnahmen und Kommentare und 4. Humane fetale Hodenkulturen und Xenotransplantate
  19. 5. Tierversuche und 6. Querbewertung: Was die Experimente tragen und was nicht
  20. 7. Überblick in Zahlen und 8. Grenzen dieses Kapitels
  21. Wie die Belegstärke in diesem Kapitel eingestuft wird bis Weg 1: Hemmung der fetalen Androgenbildung und Androgenwirkung (antiandrogene Wege)
  22. Weg 2: Schädigung des Sertoli-Zell-Systems und des Keimzellpools bis Weg 6: Plazenta, fetales Wachstum und Luftschadstoffe (indirekte Wege)
  23. Weg 7: Persistente Stoffe: PFAS, PCB und Dioxine (Rezeptor- und Keimzellwege) bis Weg 12: Gemeinsame familiäre und soziale Faktoren als Alternativerklärung
  24. Zusammenschau: Wo die Wege zusammenlaufen und wo sie sich widersprechen bis Grenzen dieses Kapitels
  25. 1. Evidenzbasis und Lesehinweise
  26. 2. Dosis-Wirkung
  27. 3. Zeitfenster der Exposition bis 7. Wo Daten fehlen
  28. 8. Gesamtbewertung
  29. Englisch und Deutsch
  30. Französisch bis Portugiesisch
  31. Spanisch
  32. Chinesisch und Japanisch
  33. Koreanisch und Russisch
  34. Arabisch und Türkisch
  35. W1. Mütterliches Rauchen: deutliche Abnahmen in Dänemark und Europa, Nullbefunde in Kalifornien und bei Ratcliffe bis W9. Mütterliches Übergewicht: Hormonmuster statt Samenbefund, und uneinheitliche Hilfsgrößen
  36. W10. PFAS, Phthalate, Bisphenole und Mischungen: gleiche Richtung bei PFOA und PFAS-Indizes, aber Nullbefunde bei PCB, DDE und Mischungen bis W17. Zusammenschau der Widersprüche
  37. Limitationen der Evidenz
  38. Offene Forschungsfragen
  39. Praktische Einordnung
  40. Glossar
  41. Quellenverzeichnis
  42. Diagramme
  43. Quellen
  44. Prüfprotokoll der Quellenkontrolle