Vollständige Liste der 242 Quellen der Studie, geordnet nach Kennung (chronologisch absteigend nach Erscheinungsjahr). Titel nicht-englischer und nicht-deutscher Originale stehen im Original, mit deutscher Übersetzung in Klammern, soweit die Quelle sie liefert. Fehlende Angaben (Journal, PMID, DOI) wurden nicht ergänzt.
[s01] Albokhadaim I (2026): Tirzepatide ameliorates type 2 diabetes-associated male reproductive dysfunction via modulation of the Nrf2/Keap1 pathway. Toxicology research 2026;15(1):tfag010. PMID 41756101; DOI 10.1093/toxres/tfag010.
[s02] Cao L, Chen Z, Li H et al. (2026): Combination of selenium and metformin mitigated testicular damage from diabetes mellitus by enhancing glycolysis via AMPK/ SIRT1 pathway. PMID 42155248; DOI 10.1016/j.jtemb.2026.127892.
[s03] Cho KH, Bahuguna A, Kim JE et al. (2026): Combination of Policosanol (Raydel®) and Atorvastatin Improve High-Density Lipoproteins and Antioxidant Abilities to Protect Vital Organs and Fertility in Hyperlipidemic/Hyperglycemic Zebrafish. PMID 41754781; DOI 10.3390/ph19020237.
[s04] Cho KH, Jeon C, Bahuguna A et al. (2026): Protective Effects of Policosanol and Atorvastatin Co-Supplementation Against High-Cholesterol and High-Galactose Diet-Induced Metabolic and Organ Dysfunction in Zebrafish. PMID 42737584; DOI 10.3390/ijms27177687.
[s05] Damkier P, van Gelder MMHJ, Huybrechts KF et al. (2026): Paternal use of metformin and risk of major congenital malformations: A meta-analysis of 4 studies. PMID 41937475; DOI 10.1002/bcp.70547.
[s06] Deameh MG, Ramez M, Rowaiee R, Bani Irshid BA, Mohamed H, Abdelshafi A, Al-Osoufi MA, Mohamed T, Hegazin SB, Raheem O (2026): Effects of glucagon-like peptide-1 receptor agonists on male reproductive hormones, semen parameters, and metabolic outcomes: a systematic review. The journal of sexual medicine 2026;23(2):qdaf381. PMID 41498523; DOI 10.1093/jsxmed/qdaf381.
[s07] El-Beheiry KM, El-Shitany NA, El-Sayad ME, Elsisi AE (2026): Potential gonadal-beneficial effect of sitagliptin against paclitaxel-induced testicular dysfunction via mediating PERK/CHOP/NLRP3/Sestrin2 signaling pathway. Scientific reports 2026;16(1):9090. PMID 41832263; DOI 10.1038/s41598-026-40511-9.
[s08] Elshazly SM, Mahmoud NM, Ahmed GA, El-Shaarawy F, Ibrahim SM (2026): Empagliflozin beyond antidiabetic effect: Amelioration of cyclophosphamide-induced testicular toxicity in rats: Orchestrating klotho/Nrf-2/PPAR-γ/NF-κB/Bax/Bcl-2 cues. Biochemical pharmacology 2026;245:117641. PMID 41412550; DOI 10.1016/j.bcp.2025.117641.
[s09] Ersoy O, Kizilay G (2026): Role of sitagliptin in diabetes-induced testicular damage via the Fas/FasL signalling pathway. Biotechnic & histochemistry : official publication of the Biological Stain Commission 2026;101(1):11-20. PMID 41250986; DOI 10.1080/10520295.2025.2583963.
[s10] Klotz T. (2026): [GLP-1 Receptor Agonists in Urology and Andrology: Indications, Opportunities and Clinically Relevant Adverse Effects]. Zentralblatt fur Chirurgie. PMID 42748969; DOI 10.1055/a-2943-1080.
[s11] Kuchakulla M, Poppas PJ, Wald G, Masterson JM, Gurayah AA, Bhambhvani HP, Kashanian JA. (2026): Impact of GLP-1 Receptor Agonists on Male Fertility: Emerging Evidence and Future Directions. Urology. PMID 41016449; DOI 10.1016/j.urology.2025.09.038.
[s12] Li ZM, Chang RY, Li R et al. (2026): Metformin mitigates oxidative stress and prevents apoptosis by modulating the Nrf2/HO-1 signaling pathway in a rat model of testicular ischemia/reperfusion. PMID 42079027; DOI 10.22038/ijbms.2026.90564.19525.
[s13] Liu S, He M, Xu H et al. (2026): Capacitation-Induced Changes in Sperm Motility, AMPK Phosphorylation, and Tyrosine Phosphorylation Are Diminished by Therapeutically Relevant Concentrations of Metformin. PMID 41628886; DOI 10.1002/jat.70088.
[s14] Mahmoud S, Abdel-Ghany RH, Elgharbawy AS, Khamis T, Zakaria EM (2026): Empagliflozin and naringenin mitigate cisplatin-induced testicular injury via modulating NLRP3 inflammasome-mediated pyroptosis: Integrated molecular docking and in vivo evidence. Reproductive toxicology (Elmsford, N.Y.) 2026;143:109259. PMID 42107736; DOI 10.1016/j.reprotox.2026.109259.
[s15] Mao J, Xu M, Tang Y et al. (2026): Gout, hyperuricemia, and male reproductive health: a systematic review and meta-analysis. PMID 42812299; DOI 10.3389/fimmu.2026.1889720.
[s16] Mohamed MH, Abd El-Rheem SM, Almadaly EA, Alkattawy AMAE, El Nasr N, Dorghamm DA, Abdo WS, Assas M, Abouzed TK, El-Domany WB (2026): Effect of ginger extract and/or fenofibrate on the associated infertility of experimentally induced obese Wistar Albino male rats. Reproductive biology 2026;26(2):101208. PMID 41861450; DOI 10.1016/j.repbio.2026.101208.
[s17] Özkoçer SE, Guney Eskiler G, Konac E (2026): Protective effects of metformin and vitamin C on diabetes-induced testicular dysfunction. Reproduction (Cambridge, England) 2026;171(6):xaag064. PMID 42172611; DOI 10.1093/reprod/xaag064.
[s18] Pan T, Fan G, Ji X et al. (2026): Paternal preconceptional metformin exposure induces metabolic dysregulation in offspring. Cell Discovery. PMID 42380093; DOI 10.1038/s41421-026-00913-5.
[s19] Peel A, Lyons H, Tully CA, Vincent AD, Jesudason D, Wittert G, McPherson NO. (2026): The effect of obesity interventions on male fertility: a systematic review and meta-analysis. Human reproduction update. PMID 41065428; DOI 10.1093/humupd/dmaf025.
[s20] Rahman MA, Harrath AH, Jalouli M et al. (2026): Targeting AMPK Networks for Male Reproductive Health: Mechanisms and Emerging Therapies. PMID 42121908; DOI 10.3390/cells15090808.
[s21] Salonia A (Chair), Boeri L, Capogrosso P, Corona G, Dinkelman-Smit M, Falcone M, Gül M, Kadıoğlu A, Minhas S (Vice-chair), Serefoğlu EC, Verze P et al. (2026): EAU Guidelines on Sexual and Reproductive Health (limited update March 2026). European Association of Urology.
[s22] Zafrani Z, Khan SS, Zitzmann M. (2026): Metabolic Reversal of Functional Hypogonadism? GLP-1 Receptor Agonists and Male Reproductive Endocrinology-A Systematic Review. Cells. PMID 42587729; DOI 10.3390/cells15151319.
[s23] Греков Е.А., Тюзиков И.А., Смирнов А.В. (2026): «Эректильная» безопасность фармакотерапии метаболического синдрома у мужчин глазами уролога-андролога („Erektile“ Sicherheit der Pharmakotherapie des metabolischen Syndroms bei Männern aus Sicht des Urologen-Andrologen). Эффективная фармакотерапия 2026;22.
[s24] Тюзиков И.А., Греков Е.А., Смирнов А.В. (2026): Репродуктивные эффекты современных гипогликемических препаратов у бесплодных мужчин с сахарным диабетом 2 типа (Reproduktive Effekte moderner hypoglykämischer Präparate bei unfruchtbaren Männern mit Typ-2-Diabetes). Эффективная фармакотерапия 2026;22(31):22-38. DOI 10.33978/2307-3586-2026-22-31-22-38.
[s25] Тюзиков И.А., Греков Е.А., Смирнов А.В. (2026): Мужские репродуктивные нарушения при сахарном диабете: патофизиологические механизмы, причинно-следственные связи и возможности эмпирической фармакотерапии (Männliche Fortpflanzungsstörungen bei Diabetes mellitus: pathophysiologische Mechanismen, Kausalzusammenhänge und Möglichkeiten der empirischen Pharmakotherapie). Эффективная фармакотерапия 2026;22.
[s26] Abdel-Wahab BA, El-Shoura EAM, Habeeb MS, Aldabaan NA, Ahmed YH, Zaafar D (2025): Unraveling the impact of semaglutide in a diabetic rat model of testicular dysfunction: Insights into spermatogenesis pathways and miRNA-148a-5p. Steroids 2025;213:109537. PMID 39551458; DOI 10.1016/j.steroids.2024.109537.
[s27] Araújo Leite GA, Lazzari VM, Simão VA, Sanabria M. (2025): Effects of statins on male reproductive health: a systematic review of rodent studies and their potential implications to human male reproduction. Critical reviews in toxicology. PMID 40568726; DOI 10.1080/10408444.2025.2504395.
[s28] Chen Y, Gu L, Xiong Y et al. (2025): Protective effects of atorvastatin on testicular dysfunction and reduced sperm quality induced by high-fat diet in mice: The inhibitory mechanism of oxidative stress. PMID 39921059; DOI 10.1016/j.ejphar.2025.177357.
[s29] Cingöz M. (2025): Dapagliflozinin Yaşlı Erkek Sıçanlarda Reprodüktif Sistem Üzerine Etkilerinin Araştırılması (Untersuchung der Wirkungen von Dapagliflozin auf das Fortpflanzungssystem alter männlicher Ratten). Abschlussarbeit, Universität Kocaeli.
[s30] Elgohary R, El-Fadaly AA, Salama A (2025): Protective Effects of Atorvastatin on LPS-Induced Testicular Damage: Modulation of Spermatogenesis via PPAR-γ, NF-κB, and NLRP3 Pathways. Journal of applied toxicology : JAT 2025;45(11):2321-2329. PMID 40611543; DOI 10.1002/jat.4851.
[s31] Elhemiely AA, Elesawy WH, Abd El Aal HA, Abdelhameed AS, Russo GI, Hassan ESG (2025): Mitigating testicular dysfunction: Metformin's role in combating valproic acid-induced damage in rats. Reproductive biology 2025;25(4):101082. PMID 41016371; DOI 10.1016/j.repbio.2025.101082.
[s32] Gregorič N, Šikonja J, Janež A, Jensterle M. (2025): Semaglutide improved sperm morphology in obese men with type 2 diabetes mellitus and functional hypogonadism. Diabetes, obesity & metabolism. PMID 39511836; DOI 10.1111/dom.16042.
[s33] Harby SA, Fathelbab MH, Nawwar BM, Sheta E, Halwag DI, Elneily DAE, Habiba ES (2025): Liraglutide and denatonium benzoate attenuate T2DM-induced metabolic, neurological, and testicular changes in rats: Targeting oxidative stress, inflammation, and BCRP transporter. Journal of molecular histology 2025;56(2):78. PMID 39881033; DOI 10.1007/s10735-025-10355-0.
[s34] Hassan NF, Khidr HY, Eltelbany RFA, Abd El-Galil MM, Reda E, El-Zohairy NA, Gowifel AMH (2025): Linking GLP-1 activation with steroidogenesis, redox, endoplasmic reticulum stress, mitophagy, and the apoptotic regulatory network unlocks the emerging impacts of semaglutide on 5-fluorouracil-induced testicular toxicity. Life sciences 2025;381:124014. PMID 41072890; DOI 10.1016/j.lfs.2025.124014.
[s35] Horst PGJT, Edens MA, Besten-Bertholee DD, Mulder LW, Curfs MHJM. (2025): Medication, age and abstinence days associated with low semen quality: A cross-sectional study in more than 7000 men visiting the centre for reproductive medicine. PloS one 2025;20(7):e0326795. PMID 40680071; DOI 10.1371/journal.pone.0326795.
[s36] Islam MA, Haque MA, Mumit Sarkar A, Rahman MS, Taufiqur Rahman AMM, Begum S. (2025): Effect of metformin on free testosterone level in male diabetic patients: A comparative study. Medicine. PMID 41204600; DOI 10.1097/md.0000000000044989.
[s37] Jiang X, Zhu Z, Liu Q et al. (2025): Shenling Baizhu San attenuates testicular spermatogenic dysfunction in hyperuricemic mice via dual modulation of MAPK/NF-κB and NLRP3 inflammasome pathways. PMID 41024187; DOI 10.1186/s41065-025-00553-x.
[s38] Karimian M, Shabani M, Nikzad H. (2025): Association of Functional Genetic Variations in Uric Acid Transporters with the Risk of Idiopathic Male Infertility: A Genetic Association Study and Bioinformatic Analysis. Biochemical genetics. PMID 39141156; DOI 10.1007/s10528-024-10902-6.
[s39] Li H, Zhang M, Ma J et al. (2025): Zinc Combined with Metformin Corrects Zinc Homeostasis and Improves Steroid Synthesis and Semen Quality in Male Type 2 Diabetic Mice by Activating PI3K/AKT/mTOR Pathway. PMID 39826075; DOI 10.1007/s12011-025-04518-z.
[s40] Li Y, Zhou T, Liu Z, Zhu X, Wu Q, Meng C, Deng Q. (2025): Protective effect of antidiabetic drugs against male infertility: evidence from Mendelian randomization. Diabetology & metabolic syndrome. PMID 40296064; DOI 10.1186/s13098-025-01700-0.
[s41] Li Z, Zhang PH, Liu MJ et al. (2025): [Statin drugs for the treatment of erectile dysfunction: An umbrella review]. (Originaltitel auf Chinesisch in PubMed nicht abgerufen; englischer Titel in eckigen Klammern). PMID 40910915.
[s42] Liu D, Han X, Zou W et al. (2025): Probiotics Combined with Metformin Improves Sperm Parameters in Obese Male Mice through Modulation of Intestinal Microbiota Equilibrium. PMID 39623123; DOI 10.1007/s43032-024-01748-9.
[s43] Lunzer R, Delle-Karth G, Zeitlinger M, Prager M, Pracher LM. (2025): [Colchicine-Phoenix from the ashes]. Wiener klinische Wochenschrift. PMID 39912853; DOI 10.1007/s00508-024-02490-7.
[s44] Luo Z, Wang L, Luo J, Shi L, Wang L, Xie G. (2025): Antidiabetic agents and male fertility: unraveling the impact of glucose-lowering therapies on sperm quality in diabetic males-a narrative review. Translational andrology and urology 2025;14(10):3387-3401. PMID 41230150; DOI 10.21037/tau-2025-440.
[s45] Ma L, Chen J, Li Q et al. (2025): Atorvastatin improves spermatogenesis in murine and in vitro human chronic orchitis models through restoring blood-testis barriers. PMID 41198620; DOI 10.1038/s41420-025-02749-6.
[s46] Otón T, Sağ E, Carmona L, Ozen S. (2025): Safety of colchicine on fertility, pregnancy, and lactation: a systematic review and meta-analysis informing the EULAR/PReS recommendations for familial Mediterranean fever. Annals of the rheumatic diseases 2025;84(6):1045-1051. PMID 40023732; DOI 10.1016/j.ard.2025.02.005.
[s47] Parlar K, Azman FN, Sıcakyüz SL, Rızaoğlu M, Azman E, Yüzbaşıoğlu MB, Korkmaz D, Uğurlu S. (2025): Fertility in male patients with familial Mediterranean fever and paternal effect of FMF on pregnancy outcomes and complications. Internal and emergency medicine. PMID 39907917; DOI 10.1007/s11739-025-03881-y.
[s48] Peng J, Wu L, Li Z, Huang Q, Li L. (2025): Density gradient centrifugation specifically improves sperm motility in hyperuricemia: evidence from intrauterine insemination cycles - retrospective cohort study. Basic and clinical andrology. PMID 41204074; DOI 10.1186/s12610-025-00292-z.
[s49] Salvio G, Ciarloni A, Ambo N, Bordoni M, Perrone M, Rossi S, Balercia G (2025): Effects of glucagon-like peptide 1 receptor agonists on testicular dysfunction: A systematic review and meta-analysis. Andrology 2025;13(8):2022-2034. PMID 40105090; DOI 10.1111/andr.70022.
[s50] Simonsen CS, Eisenberg ML, Lindahl-Jacobsen R. (2025): Paternal exposure to antidiabetic medications during reproductive period and adverse birth outcomes: A meta-analysis and systematic review. European journal of obstetrics, gynecology, and reproductive biology 2025;315:114747. PMID 41046848; DOI 10.1016/j.ejogrb.2025.114747.
[s51] Ursavas S, Kuyucu Y, Yenilmez ED, Tuli A, Tekayev M, Mete UO (2025): The evaluation of the effects of metformin on the rat testes at a light and electron microscopic level. Biochemical and biophysical research communications 2025;753:151507. PMID 39983548; DOI 10.1016/j.bbrc.2025.151507.
[s52] Yin D, Li F, Xia L et al. (2025): GLP-1 receptor agonists show no detrimental effect on sperm quality in mouse models and cell lines. PMID 40347306; DOI 10.1007/s12020-025-04245-4.
[s53] Yıldırım B, Baygül O, Şengün N, Üstündağ ÜV, Ateş N, Balçıkanlı Z, Beker MÇ, Keskin İ, Kılıç E (2025): HMG-CoA reductase inhibition preserves testicular function after torsion/detorsion by modulating oxidative stress and AKT signaling. Scientific reports 2025;15(1):45023. PMID 41274952; DOI 10.1038/s41598-025-29283-w.
[s54] Zhang M, Li H, Ma J et al. (2025): Effects of Zinc Combined with Metformin on Zinc Homeostasis, Blood-Epididymal Barrier, and Epididymal Absorption in Male Diabetic Mice. PMID 38589680; DOI 10.1007/s12011-024-04171-y.
[s55] Раевский К.П., Нестерова О.Ю., Стригунов А.А., Чалый М.Е., Кадрев А.В., Плисюк А.Г., Камалов А.А., Орлова Я.А. (2025): Рандомизированное конТРолируемое Исследование влияния СТатинотерапии на АНдрогенный статус и эректильную функцию у мужчин с высоким и очень высоким сердечно-сосудистым риском (ТРИСТАН): протокол и обоснование исследования (Randomisierte kontrollierte Studie zum Einfluss der Statintherapie auf Androgenstatus und Erektionsfunktion bei Männern mit hohem und sehr hohem kardiovaskulärem Risiko (TRISTAN): Protokoll und Begründung der Studie). Рациональная фармакотерапия в кардиологии 2025;21(2):126-131. DOI 10.20996/1819-6446-2025-3145.
[s56] Abd-Elhakim YM, El-Fatah SSA, Behairy A, Saber TM, El-Sharkawy NI, Moustafa GG, Abdelgawad FE, Saber T, Samaha MM, El Euony OI (2024): Pumpkin seed oil lessens the colchicine-induced altered sex male hormone balance, testicular oxidative status, sperm abnormalities, and collagen deposition in male rats via Caspase3/Desmin/PCNA modulation. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024;193:115029. PMID 39362398; DOI 10.1016/j.fct.2024.115029.
[s57] Alyami NM, Alnakhli ZA, Alshiban NM, Maodaa S, Almuhaini GA, Almeer R, Alshora D, Ibrahim M (2024): Oral administration of proniosomal glibenclamide formulation protects testicular tissue from hyperglycemia fluctuations and ROS via Nrf2/HO-1 pathway. Heliyon 2024;10(10):e31283. PMID 38813164; DOI 10.1016/j.heliyon.2024.e31283.
[s58] Capelo MF, Monteiro PB, Anastácio BM. (2024): Effects of major analgesics on male fertility: A systematic literature review. JBRA assisted reproduction. PMID 38546117; DOI 10.5935/1518-0557.20240020.
[s59] Chihaoui M, Terzi A, Hammami B, Oueslati I, Khessairi N, Chaker F, Yazidi M, Feki M. (2024): Effects of high-intensity statin therapy on steroid hormones and vitamin D in type 2 diabetic men: A prospective self-controlled study. Lipids. PMID 38764377; DOI 10.1002/lipd.12399.
[s60] de Mello TF, Goedert AB, de Souza JSS, da Cruz JVR, da Silva AS, Knorst JK, Muller YMR, Silva FRMB, Leite GAA. (2024): Prolonged exposure to rosuvastatin from pre-puberty to adulthood impairs sperm quality in mice and leads to paternally mediated developmental toxicity. Reproductive toxicology (Elmsford, N.Y.). PMID 39276807; DOI 10.1016/j.reprotox.2024.108717.
[s61] Dong J, Tong X, Xu J et al. (2024): Metformin improves obesity-related oligoasthenospermia via regulating the expression of HSL in testis in mice. PMID 38367685; DOI 10.1016/j.ejphar.2024.176388.
[s62] Farooqui N, Khan S, Zahid N, Nazim SM, Tahir M, Rehman R. (2024): Role of metformin in male oxidative stress infertility (MOSI): An in vitro experimental study. Pakistan journal of pharmaceutical sciences. PMID 39340857.
[s63] Glina FPA, Lopes L, E Silva RS, Barros EAC, Biselli B, Glina S. (2024): Do statins decrease testosterone in men? Systematic review and meta-analysis. International braz j urol : official journal of the Brazilian Society of Urology. PMID 38386784; DOI 10.1590/s1677-5538.ibju.2023.0578.
[s64] Hussein RS, Eyada MM, Mostafa RM, Elaidy SM, Elsayed SH, Saad HM (2024): Impact of carbimazole combined with vitamin E on testicular injury induced by experimental hyperthyroidism in adult albino rats: oxidative/inflammatory/apoptotic pathways. Asian journal of andrology 2024;26(4):396-401. PMID 38639715; DOI 10.4103/aja202365.
[s65] Iida M, Asano A (2024): Effects of glucagon-like peptide-1 receptor agonists on spermatogenesis-related gene expression in mouse testis and testis-derived cell lines. PMID 38556323; DOI 10.1292/jvms.24-0042.
[s66] Ji X, Yu L, Han C et al. (2024): Investigating the effects of rare ginsenosides on hyperuricemia and associated sperm damage via nontargeted metabolomics and gut microbiota. PMID 38768838; DOI 10.1016/j.jep.2024.118362.
[s67] Jin Z, Cao Y, Wen Q et al. (2024): Dapagliflozin ameliorates diabetes-induced spermatogenic dysfunction by modulating the adenosine metabolism along the gut microbiota-testis axis. PMID 38182877; DOI 10.1038/s41598-024-51224-2.
[s68] Kosinski C, Papadakis GE, Salamin O, Kuuranne T, Nicoli R, Pitteloud N, Zanchi A. (2024): Effects of empagliflozin on reproductive system in men without diabetes. Scientific reports. PMID 38877312; DOI 10.1038/s41598-024-64684-3.
[s69] Li C, Wang Y, Mu R, Zhao J, Yao Z, Zhai J, Jin Y, Liu R, Liu D, Hong K, Jiang H, Zhang Z. (2024): Urate-lowering agents do not have clinically relevant negative effects on sperm quality and reproductive hormones in men with gout: a prospective open-label cohort study. Rheumatology international 2024;44(7):1245-1253. PMID 38538820; DOI 10.1007/s00296-024-05572-x.
[s70] Li W, Li H, Zha C et al. (2024): Lipids, lipid-modified drug target genes, and the risk of male infertility: a Mendelian randomization study. PMID 39114294; DOI 10.3389/fendo.2024.1392533.
[s71] Li Y, Meng C, Zhou T, Liu Z, Wu Q, Zhu X, Deng Q. (2024): Causal relationship between serum uric acid levels and male infertility: a bidirectional two-sample Mendelian randomization study. Translational andrology and urology. PMID 39698557; DOI 10.21037/tau-24-365.
[s72] Liu YF, Wang HH, Geng YH, Han L, Tu SH, Chen JS, Wen CY. (2024): Uncovering the Potential Mechanisms and Effects of Hyperuricemia and its Associated Diseases on Male Reproduction. Reproductive sciences (Thousand Oaks, Calif.). PMID 38379071; DOI 10.1007/s43032-024-01453-7.
[s73] Meng LC, van Gelder MMHJ, Chuang HM, Chen LK, Hsiao FY, Nordeng HME. (2024): Paternal metformin use and risk of congenital malformations in offspring in Norway and Taiwan: population based, cross national cohort study. BMJ (Clinical research ed.) 2024;387:e080127. PMID 39414354; DOI 10.1136/bmj-2024-080127.
[s74] Mu Y, Luo LB, Huang R et al. (2024): Cardiac-derived CTRP9 mediates the protection of empagliflozin against diabetes-induced male subfertility in mice. PMID 39392219; DOI 10.1042/cs20241477.
[s75] Mu Y, Luo LB, Wu SJ et al. (2024): Bezafibrate alleviates diabetes-induced spermatogenesis dysfunction by inhibiting inflammation and oxidative stress. Heliyon. PMID 38533024; DOI 10.1016/j.heliyon.2024.e28284.
[s76] Ni F, Wang F, Li J et al. (2024): BNC1 deficiency induces mitochondrial dysfunction-triggered spermatogonia apoptosis through the CREB/SIRT1/FOXO3 pathway: the therapeutic potential of nicotinamide riboside and metformin†. PMID 38079523; DOI 10.1093/biolre/ioad168.
[s77] Oltulu C, Ersoy O, Akinci M, Cevikelli-Yakut ZA, Dasman M, Bakar E (2024): Effects of sitagliptin and L-theanine combination therapy on testicular tissue in rats with experimental diabetes. Toxicology and applied pharmacology 2024;492:117119. PMID 39378959; DOI 10.1016/j.taap.2024.117119.
[s78] Qi R, Liang Y, Yu J et al. (2024): Liraglutide improved the reproductive function of obese mice by upregulating the testicular AC3/cAMP/PKA pathway. PMID 38509558; DOI 10.1186/s12958-024-01202-0.
[s79] Qu W, Xu Y, Yang J et al. (2024): Berberine alters the gut microbiota metabolism and impairs spermatogenesis. PMID 39420836; DOI 10.3724/abbs.2024174.
[s80] Rotem RS, Weisskopf MG, Huybrechts KF, Hernández-Díaz S. (2024): Paternal Use of Metformin During the Sperm Development Period Preceding Conception and Risk for Major Congenital Malformations in Newborns. Annals of internal medicine 2024;177(7):851-861. PMID 38885501; DOI 10.7326/m23-1405.
[s81] Schlegel PN, Sigman M, Collura B, De Jonge CJ, Eisenberg ML, Lamb DJ, Mulhall JP, Niederberger C, Sandlow JI, Sokol RZ, Spandorfer SD, Tanrikut C, Zini A; Amendment: Brannigan RE, Tanrikut C (2024): Diagnosis and Treatment of Infertility in Men: AUA/ASRM Guideline 2020; Amended 2024. American Urological Association / American Society for Reproductive Medicine.
[s82] Su Q, Wang R, Luo Y, Tang Q, Wang K. (2024): Genetic association of lipid-lowering drug target genes with erectile dysfunction and male reproductive health. Frontiers in endocrinology. PMID 38390206; DOI 10.3389/fendo.2024.1362499.
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